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Alcohol use disorder (AUD) is the most common form of addiction in Michigan and across the United States. What often starts as social drinking can develop into physical dependence that requires medically supervised detox.

Heroin is a highly addictive opioid derived from morphine. Nearly all heroin sold in Michigan today is contaminated with fentanyl, dramatically increasing the risk of fatal overdose.

Fentanyl is a synthetic opioid 50–100 times stronger than morphine. As little as 2 milligrams can be fatal. It now drives the majority of overdose deaths in Michigan.

Cocaine is a powerful stimulant that produces short-lived euphoria and long-lasting damage to the heart and brain. Crack cocaine, the smokeable form, is even faster acting and more addictive.

Methamphetamine is a highly addictive stimulant that damages the brain's dopamine system. Recovery is possible but usually requires long-term treatment and mental health support.

Prescription opioids like OxyContin, Percocet, Vicodin, and Dilaudid are effective pain relievers but carry a high risk of dependence. Many people who develop opioid use disorder started with a legitimate prescription.

Benzodiazepines — Xanax, Klonopin, Ativan, Valium — are prescribed for anxiety, panic disorder, and insomnia. Long-term use produces strong physical dependence, and stopping abruptly can be life-threatening.

Cannabis is legal for adult recreational use in Michigan, but roughly 1 in 10 users develop a use disorder. High-THC concentrates and daily heavy use raise the risk, especially for teens and young adults.

Prescription drug misuse spans opioids, benzodiazepines, stimulants, sleep aids, and muscle relaxants. What starts as taking "a little more than prescribed" can quickly become dependence.

Adderall, Vyvanse, and Ritalin are prescribed for ADHD but widely misused for studying, weight loss, and productivity. Non-medical use is particularly common on Michigan college campuses.

Xanax (alprazolam) is one of the most prescribed and most misused benzodiazepines. Its short half-life produces intense withdrawal that can trigger seizures within 24 hours of stopping.

Suboxone (buprenorphine/naloxone) is a life-saving Medication-Assisted Treatment for opioid use disorder. Some patients want to eventually taper off, which should always be done gradually and with medical support.

Kratom is a plant-based substance sold openly in Michigan smoke shops and gas stations. It acts on opioid receptors and can produce physical dependence, particularly at heavy daily doses of extract products.

LSD, psilocybin mushrooms, MDMA, ketamine, DMT, and PCP are grouped as hallucinogens. Most are not physically addictive, but psychological dependence and mental-health crises do occur.

Polysubstance use — combining opioids and stimulants, alcohol and benzos, or fentanyl with anything — is now the norm in most Michigan overdose deaths. Treatment must address every substance in play.

Oxycodone is a prescription opioid found in OxyContin, Percocet, and Roxicodone. Even patients taking it exactly as prescribed can develop physical dependence within weeks, and many people who later use heroin or fentanyl started with oxycodone.

Crack is the smoked, freebase form of cocaine. The rush is faster and more intense than powder cocaine and the crash is harder, which drives a rapid cycle of use and makes dependence develop quickly.

Dual diagnosis — also called co-occurring disorders — means a person is dealing with a substance use disorder alongside a mental health condition such as depression, anxiety, PTSD, bipolar disorder, or ADHD. Treating one without the other rarely works.

Benzodiazepines — Xanax, Klonopin, Ativan, Valium — are prescribed for anxiety, panic disorder, and insomnia. Dependence can develop in a matter of weeks, and abrupt discontinuation can cause life-threatening seizures. Medically supervised tapering is essential.

The Metro Detroit region — Wayne, Oakland, and Macomb counties — is home to more than 4 million residents and the state's densest concentration of addiction treatment providers, hospitals, and support communities.

Grand Rapids and the surrounding Kent and Ottawa county communities anchor West Michigan's rapidly growing recovery ecosystem, including major hospital systems and an established sober-living community.

Michigan's capital region combines a large college-town population with rural counties, giving it a broad mix of treatment options from Michigan State's collegiate recovery to state-run inpatient programs.

Home to the University of Michigan and Michigan Medicine, the Ann Arbor area is a national hub for addiction medicine research, MAT prescribing, and dual-diagnosis care.

Flint and the surrounding Genesee County communities have expanded outpatient MAT and harm-reduction services in response to one of Michigan's highest per-capita opioid overdose rates.

The Kalamazoo–Portage metro brings together Western Michigan University, Bronson Healthcare, and Ascension Borgess to offer a dense mix of adolescent, adult, and dual-diagnosis addiction programs.

Saginaw County anchors mid-Michigan's tri-cities region and offers a growing network of MAT clinics, residential treatment, and peer recovery services.

Muskegon County on Lake Michigan's shoreline offers a growing continuum of care from detox through sober living, with strong ties to the West Michigan recovery community.

Bay City sits within the Saginaw-Bay-Midland tri-cities corridor, giving residents access to a wide range of inpatient, outpatient, and MAT programs within short driving distance.

Midland's MyMichigan Health system anchors a growing set of outpatient and residential options for the greater tri-cities area.

Traverse City is the primary recovery hub for northern Lower Michigan, drawing patients from a wide catchment across Grand Traverse, Leelanau, Benzie, and Antrim counties.

Battle Creek and Calhoun County provide a range of addiction services from residential care to the Battle Creek VA Medical Center's veteran-focused programs.

Jackson County offers outpatient MAT, county-based mental health services, and residential treatment centered around Henry Ford Allegiance Health.

Monroe County residents can access both local outpatient and MAT services and the full spectrum of programs across Metro Detroit and Toledo.

Marquette anchors addiction care for Michigan's central and western Upper Peninsula, with UP Health System and specialized rural telehealth MAT.

Sault Ste. Marie is the primary treatment hub for Michigan's eastern Upper Peninsula, with tribal and federal treatment resources serving a large rural region.

Iron Mountain and Kingsford, along with the Oscar G. Johnson VA Medical Center, are the key addiction care access points for the western Upper Peninsula.